Summary: This paper is a research highlight of a recently published article whereby Dmitrieva-Posocco et al. (2022) showed that the Ketogenic Diet can exert strong benefits in the prevention and treatment of colorectal cancer (CRC). CRC is one of the most common cancers in the world and a large threat to human health. Multiple research has shown that unhealthy dietary patterns combined with a higher body mass index and energy intake increases the risk of CRC. The foods typically included as unhealthy are starchy foods, sugary drinks, salty snacks, processed meat and refined carbohydrates. Dmitrieva-Posocco et al.’s research detected the effect of dietary intervention on CRC growth on mice, by providing constant protein and different fat-to-carbohydrate ratios. They observed an inhibitory effect on the growth of the tumour that enhanced gradually with the increase of fat and lower carbohydrate ratios, especially in the group including 90% fat content (indicating the ketogenic diet). In summary, the work by Dmitrieva-Posocco et al. revealed a potential mechanism that the Ketogenic Diet limits the growth of colon cancer which provides new insight for treatment and therapy.
Not provided – this is a highlight review of a closed access study
Article Publication Date: 02.08.22