Gluten-Free Casein-Free Diet

Processed foods, pesticides, medications, and toxins damage the gut microbiome which in turn drives a range of digestive, autoimmune and neurological illness.  Various “Healing diets” work to heal the gut and calm the immune system and vary depending on the gut, genetics and environment.


Gluten-Free Casein-Free Diet

Gluten-Free Casein-FreeAdopting a Gluten-Free Casein-Free (GFCF) diet is a common approach to take whilst treating children with autism.

Leading researchers are seeing nearly 100% correlation between gluten and casein sensitivity in an individual, most likely because the protein molecules in wheat (gluten) and dairy (casein) have a similar molecular structure.

There is also emerging research that damage to the gut microbiome may play a role in an inability to break these proteins down.

The Theory Behind the Gluten-Free Casein-Free Diet

The theory behind using a gluten-free casein-free diet for autism is that if a person is experiencing gastrointestinal reactions to gluten and/or casein, it will cause inflammation and damage to the intestinal tract. The inflammation, in turn, may cause nutrient absorption issues, as well as intestinal hyperpermeability or ‘leaky gut’.

Leaky gut can result in large molecules being absorbed into the bloodstream, which are not normally able to pass through. Increased absorption of gluten, casein and their metabolites into the bloodstream and potentially across a ‘leaky’ blood-brain-barrier, in combination with a pre-existing metabolic defect, may worsen autistic symptoms.  These molecules may interact with a child’s brain and pose negative effects on their mood, and general wellbeing, further provoking anxiety, sensory issues, mental difficulties and worsening behavioral symptoms.

Additionally, abnormal metabolism of gluten and casein may also result in excess opioid activity in the central nervous system, altering its function and causing negative effects on mood and behavior.

Casein is also rich in glutamate, an excitatory neurotransmitter which can also increase anxiety.

Eating a gluten-free diet

The gluten-free diet was developed for people with coeliac disease, an autoimmune condition where the immune system reacts to gluten, a protein found in certain grains (wheat, oats, barley, rye). This immune reaction causes damage to the inner wall of the small intestine, in turn, flattening intestinal villi, which are responsible for nutrient absorption. Flattening of the intestinal villi may lead to multiple nutritional deficiencies, as the surface area of the gut becomes greatly reduced. Malabsorption issues usually accompany this.

A diet that is free from gluten strictly omits all gluten-containing grains and their derivatives. It aims to aid with intestinal healing, allowing the villi to grow back, and for nutrient absorption to be optimized.

What is gluten?

Gluten is a rubbery protein present in wheat, rye, barley, and oats as well as other ingredients which are derived from these grains. It is in obvious foods such as breads, pizza, pastas, porridge, cakes, pastries, noodles, and cereals. However, it is also present in some commercial products such as sauces, non-dairy creamers, malt drinks, some chocolates, beer, gravy, mayonnaise, stocks, and it may even be found in some processed meats.

How do I know if something is gluten-free?

In supermarkets, health food stores and grocers, you can identify whether or not a food contains gluten if it fits into one of these 3 categories:

1. Naturally gluten-free foods

These include:

  • All fresh fruit and vegetables
  • Nuts and seeds
  • Unprocessed meat, poultry, and seafood
  • Eggs
  • Legumes
  • Oils
  • Herbs (oregano, thyme, basil, dill, sage, coriander etc…)
  • Spices (chilli, cloves, star anise, cardamom, coriander, cinnamon, ginger, saffron, turmeric etc…)
  • Alternatives to gluten-containing grains: Rice, buckwheat, millet, quinoa, amaranth, tapioca, sago, sorghum, arrowroot.

2. Foods which are labelled “gluten-free”

These may include gluten-free:

  • Cereals
  • Bread
  • Sauces
  • Noodles
  • Pasta
  • Beverages (including alcoholic beverages like beer)

3. Gluten-free products by ingredients

If a product is not labelled gluten free, it does not necessarily mean that it contains gluten. A lot of products in supermarkets or health food stores do not have a gluten-free label placed on them, and it may be worth reading the list of ingredients to check if it does or does not contain gluten.

In Australia, under the Food Standards Code, any ingredient derived from wheat, oats, rye, or barley must be declared. Ingredients, where the source grain is not identified, will be from a grain which does not contain gluten and therefore, it can be assumed that the food is gluten-free. Essentially if you do not see wheat, rye, oats, or barley on a food label, none of the ingredients in that product are derived from a gluten-containing grain.

Eating a casein-free diet

Casein is a protein, found in the milk of mammals. This differs to lactose, the sugar component of milk. Eliminating casein from the diet requires omitting all dairy products. However, each case must be assessed individually in order to determine whether the benefits of breastfeeding outweigh the effects of casein on the child.

Foods to eliminate include:

  • Milk
  • Cream
  • Butter
  • Yoghurt
  • Cheese
  • Ice cream
  • Custard

Some ingredients containing casein include:

  • Magnesium caseinate
  • Brown sugar flavoring
  • Caramel flavoring
  • Chocolate flavoring
  • Non-dairy substitutes containing caseinates
  • Artificial butter flavor

What can be eaten on the Gluten-Free Casein-Free diet?

Eggs

Meat, Fish Poultry

Grains

Allowed All, raw or cooked. Fresh meat

Fish

Seafood

Poultry

Rice (white, brown, red, wild, sticky)

Buckwheat

Millet

Quinoa

Sorghum

Amaranth

Teff

Gluten-free noodles

Gluten free pasta

Sweet potato

 

Avoid Eggs in gluten or dairy-based sauces. Eg: Wheat-based white sauce Pre-prepared meats

Cured Meats

Luncheon meats and sausages containing
wheat, rye, oats, barley.

Wheat

Barley

Oats

Spelt

Kamut

Rye

Cous Cous

Semolina

Pasta and gnocchi

 

Vegetables

Fruit

Allowed All vegetables

Fresh, canned, frozen, dried peas, beans and lentils

All fresh canned, frozen and stewed fruit.
Avoid Creamed vegetables in gluten-containing sauce (eg: grain thickeners)

Vegetables in cream sauce

Some baked beans

Some commercially prepared vegetables and salads

Thickened fruit sauces

Pie fillings

Dried fruit dusted with flour

 

One day on the Gluten-Free Casein-Free diet

Breakfast

Lunch

Dinner

Snacks

Eggs

Greens

Gluten free bread

Avocado

Meat

Salad

Quinoa/Brown rice

Grilled fish

Sautéed vegetables

Coconut yoghurt
and berries

 

Fruit

Nuts and seeds

Hummus dip

Rice or corn crackers

 

 

References:

NOTE: Few studies can be regarded as providing extensive and sound scientific evidence for a GFCF diet. More thorough research is needed. However, based on the feedback from qualified paediatricians and other practitioners who are experienced in dietary guidance this article is presented as a resource for consideration. You should consult your clinician before considering this diet.

Research – note these references do not necessarily advocate a GFCF diet – but are provided for further reading and a broader context…

A review of gluten- and casein-free diets for the treatment of autism: 2005–2015: https://www.dovepress.com/a-review-of-gluten–and-casein-free-diets-for-treatment-of-autism-2005-peer-reviewed-fulltext-article-NDS

Note this report’s conclusion: While strong empirical support for the GFCF diet in ASD is currently lacking, studies point to the need for identifying subsets of individuals (eg, those with documented gastrointestinal abnormalities) who may be the best responders to the GFCF diet. Identifying these subsets is critically needed to enhance rigor in this research area. Until rigorous research supporting the use of GFCF diet is reported, clinicians should continue to use caution and consider several factors when advising regarding the implementation of the GFCF diet for individuals with ASD.

Mari-Bauset S, Zazpe I, Mari-Sanchis A, Llopis-G A, Morales-Suarez-Varela M, 2014, ‘Evidence of the Gluten-Free and Casein-Free Diet in Autism Spectrum Disorders: A Systematic Review’, Journal of Child Neurology, 29(12), 1718-1727

Piwowarczyk A, Horvath A, Lukasik J, Pisula E, Szajewska H, 2017, ‘Gluten and casein free diet and autism spectrum disorders in children: a systematic review’, European Journal of Nutrition, 1-8.

 

Diet Profile Research and Writing: Kimberly Kushner BHSc (Nutritional Medicine), BHSc (Naturopathy) for MINDD

Mindd Foundation